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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
21.82
Human Site:
S543
Identified Species:
43.64
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
S543
S
K
V
N
S
V
G
S
S
S
T
S
S
S
G
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
S544
S
K
V
N
S
V
G
S
S
S
T
S
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
S527
S
K
V
N
S
V
G
S
S
S
T
S
S
S
G
Dog
Lupus familis
XP_538964
685
76968
S596
S
K
I
N
S
V
G
S
G
S
T
S
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
S540
S
K
I
T
S
V
G
S
G
S
A
S
S
S
G
Rat
Rattus norvegicus
Q62726
629
70550
S540
S
K
I
T
S
V
G
S
G
S
T
S
S
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
G537
N
T
A
G
S
L
E
G
Y
A
S
Y
N
Q
H
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
Q211
P
G
D
S
E
I
D
Q
L
F
R
I
F
R
T
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
L543
Q
R
I
Q
L
A
P
L
G
H
Q
H
A
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
E483
N
L
V
G
Q
S
V
E
K
Y
E
E
F
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
Y490
F
Y
M
G
K
A
R
Y
L
P
G
S
N
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
M356
L
R
N
V
S
Q
D
M
S
E
N
F
L
F
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
6.6
N.A.
0
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
40
N.A.
13.3
20
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
17
0
0
0
9
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
9
0
0
0
17
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
0
0
9
0
9
9
0
9
9
9
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
0
9
17
9
0
% F
% Gly:
0
9
0
25
0
0
50
9
34
0
9
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
9
% H
% Ile:
0
0
34
0
0
9
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
50
0
0
9
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
9
9
0
0
9
9
0
9
17
0
0
0
9
9
0
% L
% Met:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
17
0
9
34
0
0
0
0
0
0
9
0
17
0
0
% N
% Pro:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% P
% Gln:
9
0
0
9
9
9
0
9
0
0
9
0
0
9
0
% Q
% Arg:
0
17
0
0
0
0
9
0
0
0
9
0
0
9
0
% R
% Ser:
50
0
0
9
67
9
0
50
34
50
9
59
50
42
0
% S
% Thr:
0
9
0
17
0
0
0
0
0
0
42
0
0
17
9
% T
% Val:
0
0
34
9
0
50
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
9
9
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _